He didn't hit the big time until 2000, when Cam'ron granted him a guest spot on S.D.E.'s "Double Up." Santana became a member of Cam'ron's Diplomats, contributed a number of verses on other MCs' tracks, and made his full-length debut with 2003's From Me to U. "Dipset (Santana's Town)," easily the best track off the release, barely dented the charts but deserved a lot better. Prior to releasing his follow-up, he remained active with the Diplomats' popular mixtapes. What the Game's Been Missing!, released in November 2005, eventually reached the Top Ten of the Billboard album chart. ~ Andy Kellman