In their relatively short existence as a band, Arcanium has earned a respectably loyal fan base throughout the state of Colorado. Touring with bands such as Megadeth, Machine Head, Bullet For My Valentine, Ill Nino, Butcher Babies, and Otep has also garnered them nationwide recognition. In addition, they have played high profile regional shows with Arch Enemy, Devil Driver, Devin Townsend Project, Mushroomhead and Static-X. The bands' forthcoming sophomore album entitled Ontogenesis was released on June 18th. 2013.

In July of 2014, Arcanium released Life Line: a retrospective compilation of all the music they recorded in the studio, demos, remixes and a new song.